Kuros Biosurgery AG

https://www.kuros.ch

Kuros is developing innovative products for tissue repair and regeneration. The company is a spin-off of the Swiss Federal Institute of Technology and is focused in the areas of medical sealants and bone healing (orthobiologics). Kuros’ most advanced product candidate has been designed to allow for rapid sealing of surgical incisions. The lead indication is sealing of the dural membrane after brain or spinal surgery. The product candidate is called KUR-023 and a European clinical study has been successfully completed. The company is aiming at obtaining a CE mark for commercialization in Europe in 2017. Kuros is planning a second clinical study to support approval for the product in the US. Kuros’ second class of product candidates is designed to generate bone tissue for difficult to heal fractures and to stabilize the spine. Kuros’ most advanced bone healing product candidates are KUR-111 and KUR-113, both of which have been tested in large, controlled Phase 2b clinical trials demonstrating efficacy by meeting the studies’ primary endpoints. KUR-111 and KUR-113 share the same biologically active agents and have been tested in clinical trials involving over 380 patients to date exhibiting an excellent safety profile. Kuros (formerly known as Kuros Biosurgery Holding Ltd.) announced in November 2015 the completion of a financing of over CHF20 million that the company expects to provide adequate financing to bring KUR-023 to market in both Europe and the US. Moreover, this financing will allow the company to prepare for a Phase 3 study with its lead product candidate for bone healing, KUR-111. In 2015, Kuros (under the name Cytos Biotechnology Ltd.) entered into two exclusive license agreements in different fields with pharmaceutical partners namely (i) an exclusive license agreement granting Arbutus Biopharma Corp.(NASDAQ: ABUS) (formally known as OnCore Biopharma) access to Kuros’ clinically validated virus -like particle (VLP) platform for use in the treatment and prevention of hepatitis B viral infections and (ii) an exclusive license agreement in the field of oncology granting Checkmate Pharmaceuticals LLC exclusive access to Kuros’ clinically validated product candidate CYT003 as well as its VLP platform and to technology related to oligonucleotide synthesis. For both collaborations, Kuros may receive development milestones and may receive up to double digit royalties on net sales from successfully developed products. *

	Start	2002-01-01 splitoff
	Group	Kuros (Group)
	Predecessor	Kuros Therapeutics AG
	Industry	BIOTECH
	Industry 2	biomaterials
	Person	Cowling, Didier (Kuros 200807 CEO)
	Person 2	Irvine, Alistair (Kuros 201508 CBO)

	Region	Zürich ZH
	Country	Switzerland
	Street	1 Technoparkstr.
	City	8005 Zürich ZH
	Tel	+41-44-200-5600
		Address record changed: 2020-12-02

Basic data	Employees	n. a.

		* Document for »About Section«:

		Record changed: 2023-07-10