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Medigene AG (FSE: MDG1, Prime Standard)
Medigene AG (FSE: MDG1) is a leading immuno-oncology company dedicated to developing T-cell therapies to effectively eliminate cancer. Its end-to-end technology platform, built on multiple proprietary and exclusive product enhancement and product development technologies, allows Medigene to create best-in-class differentiated, T Cell Receptor engineered T cell (TCR-T) therapies for multiple solid tumor indications that are optimized for both safety and efficacy. This platform provides product candidates for both its in-house therapeutics pipeline and partnering. For more information, please visit medigene.com About Medigene’s TCR-T Therapy Platform Medigene’s immunotherapies help activate the patient’s own defense mechanisms by harnessing T cells in the battle against cancer. Medigene’s end-to-end platform combines multiple exclusive and proprietary technologies to create best-in-class TCR-T therapies. The platform includes multiple product enhancement technologies, (e.g. PD1-41BB Switch Receptor, Precision Pairing) and development optimization technologies (e.g. Allogeneic-HLA (Allo-HLA) TCR Priming) to aid the development of differentiated TCR-T therapies. Partnerships with multiple companies including BioNTech, 2SeventyBio, and Hongsheng Sciences, continue to validate the platform’s assets & technologies. About Medigene’s MDG1015 Program MDG1015 is a 3rd generation T cell receptor engineered T cell (TCR-T) therapy targeting NY-ESO-1, a well-recognized and validated cancer testis antigen which is expressed in multiple tumor types. MDG1015 contains our high-avidity, NY-ESO-1 TCR combined with our proprietary PD1-41BB co-stimulatory switch receptor that blocks the PD1/PD-L1 inhibitory axis while simultaneously activating the T cell through the well described -41BB pathway further enhancing the activity and persistence of the TCR-T in the hostile tumor microenvironment (TME). MDG1015 is currently undergoing IND/CTA enabling studies. *
Start | 1994-01-01 established | |
Group | Medigene (Group) | |
Industry | pharmaceutical | |
Industry 2 | TCR engineered T-cells | |
Person | Ho, Selwyn (Medigene 202207– CEO before Connect Biopharma) | |
Person 2 | Schendel, Dolores J. (Medigene 202207– CSO + Head of RnD before CEO + CMO + Triant + HelmholtzZentrum München) | |
Region | Martinsried | |
Country | Germany | |
Street | 11 Lochhamer Str. | |
City | 82152 Martinsried | |
Tel | +49-89-8565-2900 | |
Address record changed: 2024-01-05 | ||
Basic data | Employees | C: 51 to 100 (2020-12-31) |
Currency | EUR | |
Annual sales | 31,247,000 (revenue, consolidated (2022) 2022-12-31) | |
Profit | -8,330,000 (2022-12-31) | |
Cash | 22,224,000 (2022-09-30) | |
* Document for »About Section«: Medigene AG. (2/1/23). "Press Release: Medigene AG Appoints Pamela Keck as Vice President of Investor Relations and Corporate Communications". Planegg. | ||
Record changed: 2023-12-30 |
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More documents for Medigene (Group)
- [1] Medigene AG. (11/21/23). "Press Release: Medigene AG Announces Prioritization of Pipeline and Resource Allocation as Well as Extension of Cash Runway". Planegg....
- [2] Medigene AG. (5/3/23). "Press Release: Medigene AG Reports Financial Results and Business Update for Q1 2023". Martinsried....
- [3] Medigene AG. (5/2/23). "Press Release: Medigene Acquires Worldwide, Exclusive License of CD40L-CD28 Costimulatory Switch Receptor". Planegg....
- [4] Medigene AG. (2/1/23). "Press Release: Medigene AG Appoints Pamela Keck as Vice President of Investor Relations and Corporate Communications". Planegg....
- [5] Medigene AG. (1/18/23). "Press Release: Medigene Receives $3 Million Milestone Payment from 2seventy bio". Planegg....
- [6] Medigene AG. (2/25/22). "Press Release: Dr. Selwyn Ho Appointed New CEO of Medigene". Lisbon....
- [7] BioNTech SE. (2/21/22). "Press Release: BioNTech and Medigene Announce Global Collaboration to Advance T Cell Receptor Immunotherapies Against Cancer". Mainz & Martinsried....
- [8] Medigene AG. (1/28/21). "Press Release: Focus on Solid Tumors – Discontinuation of MDG1021 Development Program". Planegg-Martinsried....
- [9] Medigene AG. (1/13/21). "Press Release: Medigene Expands Patent Protection of Its Technologies in Key Markets, the USA and Europe". Planegg-Martinsried....
- [10] Medigene AG. (11/12/20). "Press Release: Medigene Provides Q3 2020 Update". Planegg-Martinsried....
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