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Pyxis Oncology (US)

Pyxis Oncology (“Pyxis”), a newly formed immuno-oncology company, launched in July 2019 with a focus on developing a new family of antibody-based immunotherapies derived from novel insights into the biology of the tumor microenvironment. Leaps by Bayer led the Company’s USD 22 million Series A financing and was joined by additional institutional and strategic investors including Agent Capital, Ipsen and Longwood Fund. Pyxis was founded by Thomas Gajewski, MD, PhD, professor of Medicine, Pathology and the Ben May Cancer Institute at the University of Chicago Medicine; Longwood Fund; and John Flavin, seasoned life sciences executive and entrepreneur; with the support of the University of Chicago Polsky Center for Entrepreneurship and Innovation. Unlike traditional immuno-oncology development programs, which in many cases originated from infectious disease inflammation models, Pyxis’s approach centers on the most relevant tumor-reactive T cells from the core of growing tumors. By focusing on the unique biology of T cells within tumors, Pyxis identified immunoregulatory targets tied directly to biology of the tumor microenvironment. Pyxis has generated data on these targets through genetic and interventional preclinical proof of concept studies that suggest the potential for new effective foundational monotherapies or use in combination with other cancer therapies. *


Period Start 2019-07-17 established
Products Industry cancer immunotherapy (immuno-oncology, I-O)
  Industry 2 antibody cancer drug
Person Person Steinberg, David (Longwood Fund 201907 Partner + CEO of Pyxis Oncology)
Region Region Boston, MA
  Country United States (USA)
  Street 800 Boylston Street
Suite 1555, Prudential Tower
  City 02199 Boston, MA
    Address record changed: 2020-12-02
Basic data Employees n. a.
Record changed: 2021-04-05


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