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Organisation › Details

OxStem (Group)

OxStem was founded in 2014 by Professor Steve Davies, Professor Dame Kay Davies, Professor Angela Russell and a number of Oxford-­-based angel investors. OxStem is positioned to transform the field of medical therapeutics for what are typically (but certainly not exclusively) age-­-related conditions, such as Dementia, Heart Failure, Macular Degeneration (the leading cause of blindness in the developed world), Diabetes and Oncology. OxStem is comprised of an internationally respected top tier scientific team with a strong track record in both translational bioscience and commercialising world-­-class scientific innovation. The idea is straightforward: to use the Stem Cell and Medicinal Chemistry expertise within Chemistry and its associated partners at Oxford to identify new classes of drugs that can re- program or stimulate existing endogenous cells – awakening previously defunct or dormant cellular processes. At present, most cell therapies are based on in vitro manipulation of the cells and transplantation into the patient. The OxStem hypothesis is that since the body has existing in situ adult stem and precursor cells, using high throughput phenotypic screens (based on cultures of tissue specific cells and targeted compound libraries), we can identify new classes of compounds that are able to stimulate these cells in situ. *

 

Period Start 2014-01-01 splitoff
  Today OxStem Ltd.
  Predecessor University of Oxford, Chemistry Department
Products Industry small-molecule drug
  Industry 2 stem cell technology
Persons Person Stein, Michael (OxStem 201605 CEO)
  Person 2 Davies, Steve (Univ Oxford 201605 Professor at Dept of Chemistry)
     
Region Region Oxford, Oxfordshire
  Country United Kingdom (GB)
  Street 12 Mansfield Road
c/o Prof. Steve Davies, Chemistry Research Labs
  City OX1 3TA Oxford, Oxfordshire
  Tel +44-1865-275-646
    Address record changed: 2020-12-02
     
Basic data Employees n. a.
     
    * Document for �About Section�: 
     
   
Record changed: 2019-05-30

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