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Organisation › Details

Constructive Biology Ltd. (Constructive Bio)

At Constructive Bio we rewrite the genome to build the biomolecules of the future. Our unique technology turns living cells into biofactories, creating sustainable new materials and therapeutics. With full control of the genetic sequence and code, we are exploring chemical space previously unreached by natural biology. Through exclusive access to breakthrough science from the MRC Laboratory of Molecular Biology, based on the research carried out by our founder Professor Jason Chin, Constructive Bio alone has the ability to rewrite entire genomes and incorporate multiple non-canonical amino acids in a single molecule. Constructive Bio is realising the full scientific and commercial potential of its technologies through its proprietary platforms. These include: Full genome synthesis: We assemble DNA into genome-scale pieces, stitching and replacing megabases of DNA inside living cells. Through this process, we create entirely new genomes from scratch, writing the genetic blueprint of cells with unprecedented flexibility and precision. Engineered protein translation: Constructive Bio synthesises proteins with expanded functions by incorporating non-canonical amino acids (ncAAs). Through reprogramming the genetic code of cells and expanding their repertoire of chemical building blocks, our technology creates biofactories for the discovery and manufacturing of novel biopolymers. These molecules have unique properties and diverse applications across science and industry, including pharmaceuticals, agriculture and biomaterials. *

 

Period Start 2022-08-03 renamed
  Predecessor Constructive Genomics Ltd.
Product Industry synthetic biotechnology
Persons Person Wlodek, Aleksandra M. (Ola) (Constructive Biology 202207– CEO before Reflection Therapeutics)
  Person 2 Chin, Jason W. K. (United Kingdom (govt) 202308 MRC + Co-Founder + CSO of Constructive Biology)
     
Region Region Little Chesterford, Saffron Walden
  Country United Kingdom (GB)
  Street Science Village, Suite 7
Chesterford Research Park
  City CB10 1XL Little Chesterford, Saffron Walden
    Address record changed: 2023-09-05
     
Basic data Employees n. a.
     
    * Document for »About Section«: Constructive Biology Ltd.. (9/24/24). "Press Release: Constructive Bio Secures $58 Million in Series A Financing". Cambridge.
     
   
Record changed: 2024-09-25

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