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Sygnis AG. (4/27/17). "Press Release: Sygnis AG Reports Financial Results for Fiscal Year 2016". Madrid & Heidelberg.

Organisations Organisation Sygnis AG (Frankfurt: LIO1; ISIN: DE000A1RFM03; Prime Standard)
  Group Expedeon (Group)
  Organisation 2 C.B.S. Scientific Company
  Group Expedeon (Group)
Products Product genomic technology
  Product 2 proteomic technology
  Index term 2 Expedeon–Genetrix (ES): investment, 201605–201608 acquisition of Expedeon Holdings Ltd by Sygnis AG for €1.7m cash + na shares
Persons Person Lanckriet, Heikki (Expedeon 201111 CEO + Founder)
  Person 2 de la Huerta Martinez, Pilar (Sygnis Pharma 201303– CEO + CFO before Genetrix CEO before Zeltia)

• Revenue increased 3-fold to €1.8 million

• Growth momentum sets stage for strong 2017 business outlook

• Operating cash flow improved by 16% with break-even projected for 2017

• Acquisition of profitable companies with highly complementary product lines

• Solid cash position through rights offering and non-dilutive government funding

• Reinforced Management team

SYGNIS AG (Frankfurt: LIO1; ISIN: DE000A1RFM03; Prime Standard) today reported results for the fiscal year ending December 31, 2016.

“The year 2016 has been transformative for SYGNIS,” said Pilar de la Huerta, Co-CEO and CBDO. “We acquired two profitable companies with product lines and sales/marketing capabilities highly complementary to SYGNIS’ own strengths. The first acquisition of Expedeon contributed to revenues as of August 2016 and significantly expanded our sales reach, particularly in the U.S. and Asia, and we expect continued growth in these regions as well as in Europe, in the year ahead.”

“The integration of both acquisitions has been completed fast and smoothly. We have been able to shape efficient teams across the different departments in the group creating a more robust and scalable operation. At the same time the sales and marketing activities have been performing well and we started benefiting from the synergies in sales channels and product compatibility. New products combined with our expanded sales activities with the enlarged product portfolio, resulted in significantly increased revenue year over year,” said Dr. Heikki Lanckriet, Co-CEO and CSO. “With innovative products on the market and in development, we are confident that we can achieve our ambitious goals for 2017 and beyond.”

2016 and first quarter of 2017 operational highlights:

• Acquisition of profitable proteomics player UK-based Expedeon Holdings Ltd., provides well-established direct sales forces in the U.S. and Europe and broadens product portfolio

• Acquisition of profitable tools company, US-based C.B.S. Scientific Company Inc. increases product offerings, strengthens North American presence

• Management team strengthened with appointment of Dr. Heikki Lanckriet as Co-CEO and Chief Scientific Officer and David Roth as CFO

• Non-dilutive R&D funding of € 1.9 million awarded from Spanish government

• Rights offering and oversubscribed private placement successfully completed

• New services, tools and kits successfully launched
o SunScript™ One Step RT-qPCR Kit
o TruePrimeTM Single Cell WGA Kit V2
o TruePrimeTM Cell-Free DNA Amplification Kit
o TruePrimeTM Liquid Biopsy Kit targeting oncology research and diagnostics
o CovCheck™ Kit for quality control of the whole genome amplification
o TrueHelix bioinformatics service platform
o TrueAdvance amplification service to address quality needs in next-generation sequencing

• Collaboration agreement with ECACC signed for licensing and distribution of Caco-2 cell line

• Second OEM deal with TANON signed, expanding market access to China

• Two patents granted (Europe, China), strengthening proteomics platform

David Roth, Chief Financial Officer, said: “We ended 2016 on a sound financial footing. We have seen quarter on quarter revenue growth throughout the year and at very healthy margins. We continue to maintain a strong cash position. Our sales and operational capacity has seen a step change with the addition of Expedeon; and we have been able to benefit from synergies through consolidating our operations. Hence on a cash basis, our operating cost base for the year is largely unchanged. We expect sales to again increase significantly in 2017; with this, and an ongoing focus on expenditure, we are working towards reaching a break even operating cash position during the final part of the coming year.”

2016 financial results:

Revenues for fiscal year 2016 increased threefold to € 1.8 million (2015: € 0.6 million), with sales increases across the product portfolio and SYGNIS workflow. Revenues in Q4 2016 were €813 thousand, accounting for 45% of annual revenues; this represented a 300% increase on Q4 2015.

The reported net loss reflects a number of non-cash fair value accounting entries as well as restructuring costs and transaction expenses, all arising on the Expedeon acquisition. The results also include a one time write off of legacy non-cash deferred tax assets in Spain.

These entries lifted the result from a loss of €2.7 million to the reported loss of €4.4 million, compared with €4.0 million in 2015. Allowing for these items, underlying performance improved strongly.
The following table shows the composition of operating income and expenses for the fiscal year 2016 split out for comparison purposes with 2015:

Fiscal year ended 31 December, 2016
€ thousand

2016 reported
Expedeon fair-value non-cash
Expedeon transaction costs
Reorganization cost
Spain deferred tax
2016 for comparison

1,789 555

Costs of goods sold

Operating expenses

Results of operating activities

Finance costs

Income tax

Net profit / loss for the period

Total assets at December 31, 2016 increased to €38.0 million reflecting the acquisition and accounting for Expedeon, compared to €14.0 million at the end of 2015.

During the year cash outflow from operating activities was €3.2 million, a significant reduction on 2015 of €3.8 million. Investing activity flows of €1.8 million (2015: €0.5 million) include €1.1 million in relation to Expedeon while flows from financing activities of €4.2 million (2015: €4.7 million) are mainly from net proceeds of the capital increase of €4.1 million:

1 January to 31 December

Net loss for the period

Changes to operating assets and liabilities and non-cash items

Cash outflow from operating activities

Interest paid

Net cash outflow from operating activities

Investing activities

Financing activities

Net change in cash and cash equivalents

Exchange differences

Cash and cash equivalents at the beginning of the period

Cash and cash equivalents at the end of the period

Cash and cash equivalents at year end 2016 stood at €3.8 million, compared to €4.6 million at year end 2015.

Outlook 2017

For the fiscal year 2017 revenues in the range of €6.5 to €7.5 million are expected. This forecast is based on continued strong organic growth of the product sales through expansion of the sales force in combination with further development of the OEM and distribution sales channels. An additional OEM contract with our Chinese partner TANON was announced in April 2017.

The company continues to invest in R&D with a focus on development of its groundbreaking TruePrime technology for high value applications such as single cell DNA analysis and liquid biopsy for early detection and monitoring of cancer.

With the increased marketing and sales activities and the broader but targeted product offering, SYGNIS intends to further strengthen its sales and customer base across the world. Provided the business continues to progress as projected, the Management Board expects to reach break-even in the second half of 2017 with strong upside potential and cash generation expected for 2018.

The Company’s 2016 Annual Report will be available online at the SYGNIS website investors’ section by May 2, 2017.

Conference call details:

SYGNIS will host a conference call (conducted in English) today, April 27, 2017, at 14:00 Central European Time (CET) to discuss the consolidated financial statements and important developments during the reporting period and to provide a strategic update and financial outlook.

Interested parties can access the conference call via the following telephone numbers:
• From Germany: +49 (0) 69 7104 45598
• From Spain: +34 91 787 0777
• From the US: +1 646 843 4608
• From the UK and other countries: +44 (0) 20 3003 2666
When prompted, please provide the password, “SYGNIS”.

The conference call, which is also being webcast, will be accompanied by a slide presentation which can be accessed during the call here.

Please dial in 5 minutes before the beginning of the event.

A conference call recording will be available in the "Investors" section of the Company’s website at

For further information, please contact:


Dr. Heikki Lanckriet
Phone : +44 1223 873 364

Pilar de la Huerta
Phone: +34 91 192 36 50

MC Services AG
Raimund Gabriel
Managing Partner
Phone: +49 89 210228 0


SYGNIS AG specializes in the development and commercialization of proprietary technologies and offers a wide range of commercial products addressing key challenges in molecular biology. With the 2016 acquisition of Expedeon Holdings, Ltd. based in the UK, SYGNIS added a complementary proteomics product portfolio. Resulting from this significant expansion, SYGNIS’ product portfolio now covers the entire workflow of molecular biology. In addition, SYGNIS acquired the profitable U.S.-based life sciences tools company C.B.S. Scientific in December 2016 to further expand its product offering. The products of SYGNIS Group are sold through a direct sales force and several distribution partners in Europe, the U.S. and Asia. SYGNIS AG has offices in Germany, Spain and the UK, production sites in the UK and the U.S. as well as sales offices in Asia. The company is listed on the Prime Standard segment of the Frankfurt Stock Exchange (Ticker: LIO1; ISIN: DE000A1RFM03).

### This publication is intended for information only and constitutes neither an offer to sell nor an invitation to buy securities. Some statements included in this press release, relating neither to proven financial results nor other historical data, should be viewed as forward-looking, i.e. not definite. Such statements are mainly predictions of future results, trends, plans or goals. These statements should not be considered to be total guarantees since given their very nature they are subject to known and unknown risks and imponderability and can be affected by other factors as a consequence of which the actual results, plans and goals of SYGNIS AG may deviate greatly from the established conclusions or implied predictions contained in such statements. SYGNIS does not undertake to publicly update or revise these statements in the light of new information or future results or for any other reason.###

SYGNIS AG, Waldhofer Str. 104, 69123 Heidelberg, Germany,, Tel.: + 49-6221- 3540-125, Fax: +49-6221- 3540-127

Record changed: 2017-05-02


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