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XL-protein GmbH. (1/9/18). "Press Release: Horizon Pharma plc and XL-protein GmbH Have Entered Into a Collaboration Agreement on a Potential Next-Generation Biologic for Uncontrolled Gout Using PASylation Technology". Freising.

Organisations Organisation XL-protein GmbH (XLp)
  Organisation 2 Horizon Pharma plc
  Today Horizon Therapeutics plc (Nasdaq: HZNP)
  Group Horizon Therapeutics (Group)
Products Product PASylation® technology
  Product 2 biopharmaceutical
Persons Person Schalper, Claus (XL-protein 201410 Managing Director (CEO) before Pieris 201101 CFO)
  Person 2 Skerra, Arne (XL-protein GmbH 201104 Managing Director)

Horizon Pharma plc (NASDAQ:HZNP) yesterday announced that it has entered into a collaboration agreement with XL-protein GmbH to identify clinical-stage program candidates that could use PASylation technology to construct a next-generation gout biologic.

PASylation technology is a biological alternative to synthetic PEGylation and is intended to extend both the half-life of uricase and the duration of treatment for people living with uncontrolled gout, and also has the potential for subcutaneous dosing.

If the agreement yields a clinical-stage candidate, Horizon Pharma will have the right to license the candidate.

About XL-protein GmbH

XL-protein is a German biotech company commercializing its ground-breaking PASylation® technology, which enables the design of biopharmaceuticals with extended plasma half-life and enhanced action. Based on a strong proprietary technology position, XL-protein focuses at the preclinical as well as clinical development of PASylated proteins in diverse disease areas. XL-protein is engaged in a growing number of partnerships with international pharmaceutical and biotech companies at various levels. For more information, please visit

XL-protein Contacts:

Claus Schalper
CEO / Managing Director
+49 8161 53730 90

Arne Skerra
Cofounder and Chairman of the Board
+49 8161 53730 91

Record changed: 2021-02-27


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