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OLS Omni Life Science GmbH & Co. KG. (10/18/18). "Press Release: CERO Is a Novel 3D Cell Cultivation System". Bremen.

Organisations Organisation OLS Omni Life Science GmbH & Co. KG
  Today Omni Life Science (OLS) (Group)
  Group Omni Life Science (OLS) (Group)
  Organisation 2 DKFZ (German Cancer Research Center, GCRC)
  Group Helmholtz-Gemeinschaft (HGF) (Group)
Products Product CERO 3D cell cultivation system
  Product 2 bioreactor
Persons Person Ketterlinus, Ralf (Omni Life Science 201402 before Bruker Daltonik GmbH LEFT 7/12)
  Person 2 Keric, Amir (OLS Omni Life Science 201810 Product Manager)

A paradigm shift in the cultivation of spheroids, organoids and tissue specimen

Today, OLS OMNI Life Science GmbH & Co KG, announced the launch of its new CERO system, a benchtop 3D incubator and bioreactor, ideally suited to culture spheroids, organoids and even human tissue specimen.

The CERO bioreactor delivers a benchtop cell culture system with controlled temperature, CO2, pH and agitation of up to four 50 ml culture vessels. Optimized protocols and automatic procedures accelerate cell expansion, differentiation and maturation for optimized cell yield, enabling reduced media consumption and increased work productivity.

What makes CERO unique is the ability to keep cells and aggregates in floatation with virtually no shear force. This feature stems from a combination of tube rotation with proprietary patented tube design, which allows for healthy long-term cultures for up to several months. This provides researchers in drug development and biotechnology valuable access to more mature and fully functional validated cells for their assays.

Prof. M. Heikenwälder, DKFZ Heidelberg, Germany:
“We were able to use CERO in our lab for many different studies, such as long term tissue cultivation or regarding analyses in the context of viral hepatitis. We found that cultivating hepatocyte spheroids in CERO considerably improves expansion, differentiation, maturation and hepatic virus infection compared to monolayer culture. Our research takes advantage of healthy cells even from long-term cultures in CERO. Moreover, we are now able to perform 3D long-term culture of human tissue specimen in CERO - a paradigm shift.”

Amir Keric, Product Manager, OLS OMNI Life Science GmbH & Co KG:
“With the exciting development of organoid systems in the past decade, stem cell research still suffers from poor or complicated, huge and expensive cell cultivation instrumentation. With CERO we provide researchers with an bioreactor that allows easy walk-away touch screen based operation and enabling effective media consumption.
CERO’s strengths however, are the breathtaking quality and health of 3D cell cultures such as organoids even after long-term cultivation. Thus, CERO enables researchers for the first time to generate highly physiological relevant cell systems for their research from a benchtop system with a small footprint.”

OLS is a manufacturer and distributor of cell culture and cell assay systems for Life Science research and drug development. Founded in 2004, OLS focuses on cutting edge solutions for applications in cell-based research, stem cell expansion and differentiation, cell counting, sample preparation and cell assays. Well over 2,000 systems are found in laboratories of the public sector, private laboratories, and laboratories of the pharmaceutical - and biotechnological industries. OLS Systems are essential tools in research, analytical and production laboratories.

For more information please call Amir Keric at +49-151 501001 76 or email

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Record changed: 2019-01-03


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