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Numab Therapeutics AG. (9/30/20). "Press Release: Numab Therapeutics Appoints Daniel Vasella as New Chairman of the Board". Wädenswil (Zurich).

Organisations Organisation Numab Therapeutics AG
  Group Numab (Group)
  Organisation 2 Novartis AG (NYSE: NVS)
  Group Novartis (Group)
Products Product ND021 (Numab, tri-specific antibody targeting PD-l1 + 4-1BB + HSA)
  Product 2 therapeutic antibody
Index term Index term Ono Pharmaceutical–Numab: antibody cancer drug, 201703– research + option agreem up to CHF258m + royalties for multi-specific antibody
Persons Person Vasella, Daniel (Novartis CEO 199612–201001 after 1/10 continues as Chairman)
  Person 2 Urech, David (Numab 201910 CEO + Co-Founder before Esbatech 2004–2010)

Numab Therapeutics AG announced today the appointment of Dr. med. Daniel Vasella, former Chairman and Chief Executive Officer of Novartis AG, as the new and independent Chairman of the Board of Numab. Dr. Vasella succeeds Dr. Oliver Middendorp, founder and current Chief Business Officer, who remains on the Board of Directors as a regular member.

“We have worked very successfully with Daniel Vasella since he joined our board in October last year, and we look forward to working even closer together in the future,” said David Urech, Ph.D., Founder and Chief ExecutiveOfficer of Numab Therapeutics.

“Numab has established itself at the forefront of multi-specific antibody development, a sector that holds promise to transform the treatment landscapes in cancer and several other disease areas with high economic burden on society. I’m glad to support the company in this highly promising period,” commented Dr. Daniel Vasella, Chairman of the Board of Numab.

Numab most recently announced the dosing of the first cancer patient with its lead compound NM21-1480 (ND021 program), a tri-specific immune-modulator that concomitantly blocks the immune-suppressive PD-(L)1 pathway and triggers the immune-stimulatory 4-1BB pathway, resultingin synergistic anti-tumor activity, locally restricted to the TME. Numab also continued to execute on its partnering strategy, which resulted in the recent expansion of its discovery alliance with Ono Pharmaceutical in oncology, and a two-product alliance with Boehringer Ingelheim, aiming at multi-specific antibodies for the therapy of retinopathy and cancer, respectively. In addition to the lead program ND021, Numab’s proprietary program ND026 (regionally partnered to Kaken) in atopic diseases is steadily progressing through preclinical development.

About Numab Therapeutics

Numab Therapeutics is an oncology-focused biopharmaceutical company based in Zurich-area, Switzerland. At Numab, we are writing the next chapter in cancer immunotherapy by creating multi-specific antibodies that enable the pursuit of novel therapeutic strategies. With our proprietary MATCH technology platform, we are fueling a new wave of multi-specific drug candidates engineered with versatility and developability in mind. Our lead product was designed to balance potent anti-tumor immunity with a desirable safety profile by targeting 4-1BB, PD-L1 and Human Serum Albumin simultaneously. We believe meeting the highest quality standards in every step of the drug design process matters and will result in better patient outcomes. For further information, visit


For Numab Therapeutics
David Urech
Chief Executive Officer

For media
Sara Michelmore or Caroline Rufo, PhD.
+1 781-235-3060

Record changed: 2020-10-26


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