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Lift BioSciences Ltd.. (2/16/23). "Press Release: LIfT BioSciences and Minaris Regenerative Medicine Enter into a Manufacturing Partnership". London & Munich.

Organisations Organisation Lift BioSciences Ltd.
  Organisation 2 Minaris Regenerative Medicine GmbH
  Group Resonac (Group)
Products Product contract manufacturing (biologicals)
  Product 2 Neutrophil Only Leukocyte Infusion Therapy (N-LIfT allogeneic innate cell therapy)
Index term Index term Lift BioSciences–Resonac: biologics contract manufacturing, 202302– collab developm + manufacturing of N-LIfT for clinical trials by Minaris RM
Persons Person Blyth, Alexander William (Alex) (Lift BioSciences 201410– CEO + Founder)
  Person 2 Kosijer, Dusan (Apceth 201705– CFO of Apceth Biopharma GmbH joined 10/16 before Accovion GmbH)

GMP N-LIfT being produced for forthcoming clinical trials

LIfT BioSciences, a pioneering pre-clinical stage company moving into first-in-human trials with The World's First allogeneic neutrophil progenitor based cell therapy for treating solid tumours, and Minaris Regenerative Medicine GmbH, a leading global contract development and manufacturing service provider for the cell and gene therapy industry, have entered into a development and manufacturing partnership for N-LIfT, LIfT’s first-in-class neutrophil progenitor based Leukocyte Infusion Therapy for the treatment of various cancer indications, including Pancreatic Cancer, Lung Cancer and other solid tumours.

Fig 1: N-LIfT is produced from a patented process using the Hemopoietic Stem Cells of 'Super Donors' with exceptional immune systems. LIfT are the first company in the world to patent utilise the benefits of only donors with exceptional immunity and no family history of cancer, because neutrophils are the most genetically heterogenous cell type in the population. Some donors neutrophils have x20 the cancer killing seen in other donors, and cancer patients neutrophils often even help tumours grow.

Under the terms of the agreement, Minaris, in conjunction with LIfT Biosciences are confident they can develop a Good Manufacturing Practice (GMP)-compliant manufacturing process to supply LIfT’s clinical trial programmes in Europe, currently anticipated to start in Q1 2024. N-LIfT is made from Immunomodulatory Alpha Neutrophils committed myeloid progenitors (IMANp) that are manufactured ex vivo from hematopoietic stem cells (HSCs) of healthy donors who exhibit exceptional innate cancer killing properties. The unique mechanism of action of N-LIfT allows the product to work effectively through the innate immune pathway as well as activating multiple other factors of the adaptive immune system.

“Following very strong preclinical results, we are now moving into producing GMP grade product as we prepare for clinical trials early next year. Our mission to destroy all solid tumours irrespective of where the tumour is or how it adapts is looking more and more achievable”, said Alex Blyth, CEO of LIfT BioSciences. “We are confident that Minaris’ extensive track record in process development, clinical, and commercial manufacturing will generate a scalable and cost-effective GMP-process and accelerate our clinical readiness.”

Dusan Kosijer, CEO of Minaris Regenerative Medicine GmbH commented: “We are excited about our partnership with LIfT BioSciences and to be contributing to scientific progress in a new field. We share LIfT’s enthusiasm about their unique IMANs and their demonstrated enhanced cytotoxic and immunomodulatory properties.”

About LIfT Biosciences

LIfT BioSciences is a pre-clinical stage company working towards first-in-human trials for our first generation ATMP, N-LIfT platform N-LIfT stands for Neutrophil based Leukocyte Infusion Therapy. The product is made from Immunomodulatory Alpha Neutrophil (IMANs) committed myeloid progenitors that are manufactured ex vivo from the HSPCs of healthy donors who exhibit exceptional innate cancer killing capabilities.


Alex Blyth, CEO
+44 (0)7718 759116

Consilium Strategic Communications
Lindsey Neville, Namrata Taak

About Minaris Regenerative Medicine

Minaris Regenerative Medicine is a global contract development and manufacturing organization (CDMO) for cell and gene therapies. We offer our clients high value clinical and commercial manufacturing services, development solutions, and technologies. We are pioneers in the field with more than 20 years’ experience providing outstanding quality and reliability. Our facilities in North America, Europe, and Asia allow us to supply life-changing therapies to patients globally. Minaris Regenerative Medicine is part of the Resonac Group.

For more information, please visit


Dr. Luc St-Onge
Global Head of Sales and Marketing
Minaris Regenerative Medicine GmbH
Phone: +49 (0)89 700 9608-0

Forward-Looking Statements

This press release contains forward-looking statements which involve known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of the Company, or industry results, to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. LIfT BioSciences does not expect to update forward-looking statements continually as conditions change.

Record changed: 2024-01-06


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