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Protagen Protein Services GmbH. (7/1/21). "Press Release: Protagen Protein Services Merges with GeneWerk to Integrate Leading Protein and Gene Therapy Analytic Platforms". Heilbronn & Boston, MA.

Organisations Organisation Protagen Protein Services GmbH (PPS)
  Today ProtaGene GmbH
  Group ProtaGene (Group)
  Organisation 2 GeneWerk GmbH
  Today ProtaGene CGT GmbH
  Group ProtaGene (Group)
Products Product proteomic services
  Product 2 private equity
Index terms Index term Zukunftsfonds Heilbronn–Ampersand: investment, 202107 acquisition of majority share in PPS from ZFHN and merger with portfolio company GeneWerk
  Index term 2 GeneWerk–Ampersand: investment, 202009 majority investment in GeneWerk GmbH by Ampersand Capital Partners
Persons Person Blüggel, Martin (Protagen Protein Services 201904 CEO + Founder)
  Person 2 Schmidt, Manfred (GeneWerk GmbH 201709 Managing Director)

- Establishes a Premier, Protein and Gene Analytic Testing Service Platform Worldwide -

Protagen Protein Services (PPS) today announced that it will merge with GeneWerk, an Ampersand portfolio company. With the addition of GeneWerk’s unique capabilities in vector safety, characterization, and functionality analysis, PPS will complement its current analytical testing offering in protein characterization identity, purity, potency and capsid loading to become a full-service partner in gene therapy testing for the biopharmaceutical industry.

Today’s announced merger creates a leading partner for the worldwide biopharmaceutical industry to benefit from the most advanced, integrated set of analytical services capabilities in biologic development, especially in gene and cell therapy-related testing, from early development through drug approval to commercialization. The combined organization will have more than 175 employees across four sites in Europe and North America.

“The combination of Protagen Protein Services (PPS) and GeneWerk will establish a leading, analytical CRO serving the most thriving and innovative therapeutic segments within the global biopharmaceutical industry. We are excited to join forces with the GeneWerk team, who have established unique, worldwide excellence in cell and gene therapy and helped to establish the industry standard of integration site analysis for all vector delivery systems,” outlined Martin Blüggel, CEO Protagen Protein Services GmbH.

“We are impressed by PPS’ scientific background and are eager to join with our scientific excellence. By integrating our analytic platforms, programs and expertise with PPS, we look forward to working closely with premier biopharmaceutical companies to design, generate and deliver integrated, best-in-class analytical data packages and strategic support along the full development spectrum from developability, lead optimization, clone selection and process development to vector safety, gene editing targets, sequence analysis and gene expression,” commented Dr. Manfred Schmidt, Managing Director and Co-Founder of GeneWerk GmbH.

As part of today’s announcement, PPS noted that it plans to significantly expand the laboratory capabilities of its US subsidiary BioAnalytix to include GeneWerk’s technology platforms and analytical capabilities in order to better serve clients located in the Boston area biotechnology hub and elsewhere in North America. Such service capabilities will include the determination of fusion sequences adjacent to known DNA or RNA fragments in minimal tissue samples down to the single cell level.

To support the integration and future growth of the combined business, PPS also announced that Ampersand Capital Partners has acquired a majority ownership stake in PPS from Zukunftsfond Heilbronn, PPS’s initial private equity investor.

Marina Pellon-Consunji, Partner at Ampersand Capital Partners, stated: “We have been looking for the right opportunity to expand the capabilities of our portfolio company GeneWerk. We are proud to partner with the PPS team and look forward to helping further build a leading provider of innovative, scientifically-differentiated testing and analytical services for large molecule therapeutics, particularly in the rapidly-growing cell and gene therapy industry.”

About GeneWerk GmbH

Founded in 2014 by Prof. Dr. Christof von Kalle, Dr. Manfred Schmidt, and Dr. Annette Deichmann with the participation of the German Cancer Research Center (DKFZ) Heidelberg, GeneWerk is a cell and gene therapy testing laboratory focused on providing preclinical and clinical trial patient sample analysis services. The company is recognized as a leading provider of vector integration site analysis (ISA) services, a method that was developed by the company’s founders and that the FDA and EMA recommend performing after the administration of both integrating and non-integrating cell and gene therapies.

About Ampersand Capital Partners

Founded in 1988, Ampersand is a middle market private equity firm with more than $2 billion of assets under management dedicated to growth-oriented investments in the healthcare sector. With offices in Boston and Amsterdam, Ampersand leverages its unique blend of private equity and operating experience to build value and drive superior long-term performance alongside its portfolio company management teams. Ampersand has helped build numerous market-leading companies across each of the firm’s core healthcare sectors. Additional information about Ampersand is available at

Record changed: 2022-02-05


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