Advertisement

Picture EBD Group BIO-Europe Spring 2019 BES Wien Partnering Opens 600x60px
Document › Details

Polyplus-transfection S.A.. (7/6/18). "Press Release: Polyplus-transfection Launches New Advanced System for Transient Protein Expression in CHO cells". Strasbourg.

Organisation Organisation Polyplus-transfection S.A.
  Group Polyplus-transfection (Group)
Products Product FectoCHO™ Expression System
  Product 2 CHO cell line
     


Polyplus-transfection SA, a biotechnology company offering innovative solutions for the delivery of nucleic acids for research, bioproduction and therapeutic applications, announces the launch of its FectoCHO™ Expression System. The new system is designed for enhanced protein production in CHO cells, showing outstanding protein yields even at low DNA amounts.

The growing need for various recombinant antibodies and other proteins in the biotechnology and biopharma sectors requires an efficient and flexible bioproduction system. “Transient expression” is a technology commonly use to introduce nucleic acids into production cell line. Current available transfection solutions are limited due to insufficient transfection efficiency resulting in low protein productivity, especially when applied to CHO (Chinese Hamster Ovary) cells.

“To overcome this issue, we have developed an advanced transient expression system, the FectoCHO™ Expression System,” stated Dr. Patrick Erbacher, CSO of Polyplus-transfection. “Our new system shows amazing protein production yields in various CHO cells.”


High productivity – even at small DNA amounts

The FectoCHO™ Expression System consists of three synergistically acting components:

FectoCHO™ CD Expression Medium
FectoPRO® Transfection Reagent
FectoPRO® Expression Booster

The FectoCHO™ CD Expression Medium is a chemically defined cell culture medium, optimized for transient gene expression. It enables fast, effortless adaptation and cultivation of various strains of CHO cells, such as CHO-K1, CHO-S and ExpiCHO™-S. The FectoPRO® Transfection Reagent, when combined with the expression medium, achieves amazing protein yields, also for small amounts of DNA transfected. The FectoPRO® Expression Booster enhances gene expression levels and boosts protein production in various CHO cells. The yields are up to four times higher compared to competitors’ expression systems.


Excellent reproducibility

FectoCHO™ Expression System components are manufactured and formulated using a highly controlled production process. This ensures excellent lot-to-lot reproducibility – for greater reliability and higher quality in bioproduction. “Increased productivity and excellent reproducibility make our new expression system an affordable and reliable solution for bioproduction processes,” said Patrick. “The system is perfectly suited to protein and antibody production – even in therapeutic applications.”

Want to know more about FectoCHO™ Expression system


About Polyplus-transfection

Polyplus-transfection SA is a biotechnology company founded in 2001 that develops, markets and sells innovative solutions for the in vivo, in vitro and ex vivo delivery of nucleic acids in research, bioproduction and therapeutics. Located close to the University of Strasbourg in Eastern France, Polyplus-transfection has been ISO 9001-certified since 2002 and supplies its proprietary range of reagents for the transfection of genes and oligonucleotides. Polyplus reagents are involved in a growing number of clinical trials worldwide. In addition, Polyplus-transfection holds a broad estate of patents and licenses in the field of nucleic acid delivery.


[Picture]
The synergistic combination of FectoPRO® reagent and FectoCHO™ CD medium outperforms its main competitor in CHO-K1 cells. © Polyplus-transfection SA

[Picture]
FectoCHO™ expression system outperforms ExpiCHO™ expression system in terms of protein production kinetics in ExpiCHO-S cells. © Polyplus-transfection SA


Press Contact

Polyplus-transfection SA
Géraldine Guérin-Peyrou
phone: +33 (0)3 90406186
e-mail: ggp@polyplus-transfection.com

   
Record changed: 2018-12-05

Advertisement

Picture EBD Group BIO-Europe Spring 2019 BES Wien Vienna Austria 273x168px

More documents for Polyplus-transfection (Group)


To subscribe to our free, monthly newsletter for the European life sciences, please send an e-mail to info@iito.de and simply fill the subject line with the word »LSE Newsletter«

To get even more information, please take a look at our [gs] professional services offering and read the gene-sensor Product Flyer [PDF file]

Advertisement

Picture [LSUS] Life-Sciences-USA.com – The Business Web Portal 600x60px




» top