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Genomics Medicine Ireland Ltd.. (8/30/18). "Press Release: Genomics Medicine Ireland and University of Cambridge Announce Multiple Sclerosis Research Collaboration". Dublin.

Organisations Organisation Genomics Medicine Ireland Ltd. (GMI)
  Group WuXi PharmaTech (Group)
  Organisation 2 University of Cambridge
Products Product genomics
  Product 2 biobank
Index term Index term Genomics Medicine Ireland–Univ Cambridge: genomics, 201808– collab using 15000 DNA-extracted MS samples from biobank of Prof Sawcer
     


Partnership Aims to Dramatically Accelerate and Increase the Power of Genomic Discovery in MS


Irish life sciences company Genomics Medicine Ireland (GMI) is to collaborate with the University of Cambridge to expand GMI’s comprehensive research examining the underlying genetic factors contributing to Multiple Sclerosis (MS).

The collaboration will leverage up to 15,000 DNA-extracted MS samples which are part of a biobank compiled by Professor Stephen Sawcer – a leading University of Cambridge academic, neurologist and geneticist – in conjunction with his team in the Department of Clinical Neurosciences. This large dataset, when combined with samples already being collated via GMI’s ongoing Irish cross-border MS research study, will result in one of the world’s largest MS-focused genomic studies ever conducted.

As with any research study, the larger the available analytical data the greater the potential outcomes, therefore this collaboration will provide an enormously increased opportunity for MS researchers to achieve meaningful results that will benefit MS patients not only in Ireland but worldwide.

MS is one of the most common disabling neurological diseases and directly affects an estimated 2.5 million people across the globe, with the majority of those affected experiencing chronic disability. Researchers will combine advanced scientific technology in genomics, the study of all of a person’s genes, together with detailed clinical information to provide insights into how and why the disease develops in the search for answers that one day might lead to the development of new therapeutics for better treatment and prevention of MS.

The University of Cambridge has a strong tradition in neuroscience having been host to the first analyses of neural signalling in the 1930s; determined the mechanisms of neuronal firing in the 1950s; and heralded some of the early theoretical approaches to the functions of neural circuitry in the 1960s. Its Department of Clinical Neurosciences is embedded within Cambridge University Hospitals at the Cambridge Biomedical Campus, allowing its research questions to stem from problems its researchers have encountered in the clinic, and to directly address the needs of patients and families. Its mission is to understand the nervous system in health and disease in order to develop new treatments for incurable neurological disorders.

Dr. Sean Ennis, Co-Founder and Chief Scientific Officer of Genomics Medicine Ireland said, “We’re really excited to collaborate with Cambridge’s Department of Clinical Neurosciences in greatly expanding our research into MS. Our enlarged dataset means that we now have a significantly greater possibility for discoveries which will benefit not only MS patients in Ireland and the UK, but across the world also.”

Professor Stephen Sawcer, University of Cambridge said, “There are hundreds of genetic variants that influence the risk of developing MS, but little is known about how they exert these effects, and we have no hard evidence about which genetic variants influence the severity of the disease or determine which treatments are best suited to each individual. With the help of GMI and genomics, we aim to close these gaps in our knowledge, so we are delighted to be participating in this research as its size and scope has the potential substantially promote the development of safe and effective rational treatments.”

Genomics Medicine Ireland is currently undertaking genomic studies across the island of Ireland. The company established Ireland’s first, purpose-built genomics sequencing laboratory earlier this year and is undertaking world-class research into major chronic diseases within oncology, neuroscience and immunology that affect hundreds of thousands of people on the island of Ireland and hundreds of millions worldwide.

- Ends -


Editors’ Notes:


The Study of Genomics

Genomics is the study of all of a person’s genes (the genome), including the interactions of those genes with each other and the person’s environment. Genomics has a critical role to play in the identification, prevention and treatment of disease and rare conditions, including the scientific study of complex diseases such as heart disease, asthma, diabetes, and cancer because these diseases are typically caused more by a combination of genetic and environmental factors than by individual genes.


About Genomics Medicine Ireland

Founded in 2015, Genomics Medicine Ireland (GMI) is an Irish life-sciences company leading large-scale, population-based genome research studies on the island of Ireland examining the relationship between genetics, health and disease. It is building a preeminent disease-specific discovery platform for population genomics. GMI works in collaboration with clinicians, patients, academic researchers and global biotech and pharmaceutical sectors to discover pathways to new treatments and new diagnostics for people both here in Ireland and around the world.

GMI’s world-class investors include ARCH Ventures, Polaris Ventures, GV and Irish sovereign investment through the Ireland Strategic Investment Fund (ISIF).

For more information visit: www.genomicsmed.ie and follow us on twitter: @GenomicsMed


About the University of Cambridge

The mission of the University of Cambridge is to contribute to society through the pursuit of education, learning and research at the highest international levels of excellence. To date, 98 affiliates of the University have won the Nobel Prize.

Founded in 1209, the University comprises 31 autonomous Colleges, which admit undergraduates and provide small-group tuition, and 150 departments, faculties and institutions. Cambridge is a global university. Its 19,000 student body includes 3,700 international students from 120 countries. Cambridge researchers collaborate with colleagues worldwide, and the University has established larger-scale partnerships in Asia, Africa and America.

The University sits at the heart of the ‘Cambridge cluster’, which employs 60,000 people and has in excess of £12 billion in turnover generated annually by the 4,700 knowledge-intensive firms in and around the city. The city publishes 341 patents per 100,000 residents.

www.cam.ac.uk

   
Record changed: 2018-09-04

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